TSUNADE'S BACKGROUND -
Tsunade is the
the First Hokage, and grandniece of the Second Hokage, leading others to call
her "Princess" (姫, Hime). She along
with Jiraiya and Orochimaru are former students of
the third Hokage(HIRUZEN SARUTOBI).
During the Second Shinobi World War , Tsunade and her former team-mates fought Hanzō, who gave them the title of Konoha's "Three Legendary
Shinobi" (伝説の三忍, Densetsu no Sannin) as a reward for surviving their battle.  On their way back to Konoha, they encountered the Ame Orphans, who Jiraiya chose to train. Throughout the war, she would become famous for frequently
counteracting Chiyo's poisoning attempts, earning contempt from Chiyo because of it. Furthermore, according to Jiraiya, Tsunade was the reason Konoha won the war.
At some point
however, on her brother's twelfth birthday, Tsunade
gave him their
grandfather's crystal necklace in the hopes that it
would help him
achieve his dream
of becoming Hokage. The next day, he died as a casualty of the war, which returned the necklace to Tsunade's
possession. This event resolved Tsunade to
advocate for the inclusion of medical-nin to be incorporated into teams that were on the battle
field. Some time afterwards, Tsunade fell in love
with a man named Dan Katō who also wanted to become Hokage. As a sign of her affection, and in
the hopes that this time it would help make his
dreams come true, Tsunade gave him the necklace
as well. Dan, too, would go on to die a bloody
death during the course of the war, once again
returning the necklace to her possession. Dan's death caused her to develop hæmophobia, which made her unfit to take part in any more battles.
With the deaths of the two she loved the most,
Tsunade came to lose faith in the title of Hokage,
believing that only fools would want such a
position. With these changes of ideals, Tsunade left
Konoha with Dan's niece, Shizune, taking her on as her apprentice.
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